There is more to know than Depomedrol!!!
1. Unique Skin-Thinnest skin of all domestic animals.
2. Primary and secondary hairs ratio (1:10-24).
Eosinophilic Granuloma Complex
Group of inflammatory lesions affecting skin, mucocutaneous junctions and oral cavity of cats, usually due to genetic, parasitic,
allergic, foreign body, viral and/or bacterial causes.
It is a syndrome, not a diagnosis.
Three variants of eosinophilic granuloma complex:
1. Indolent ulcer
2. Eosinophilic plaque
3. Eosinophilic granuloma
Ulcerated lesion of upper lip.
Alopecia, raised border.
Blood and tissue eosinophilia is rare.
Moist alopecic papules and plaques.
Usually abdomen but maybe on neck.
Severe pruritus is usally associated.
Blood and tissue eosinophilia.
Pink to yellow raised plaque which maybe linear.
Usually on caudal thigh of young cats.
Younger and female cats predisposed.
Focal collagen degeneration.
This is most common underlying cause.
Atopy, food allergy, mosquitoes.
Depomedrol: every 2- weeks for 3 treatments.
Antibiotics, especially Ditrim 120mg or Clavamox.
Alpha-interferon 30-60 U PO/day, 7 days on, 7 days off.
Intradermal allergy test- Allergy vaccine therapy.
Oral Prednisone tapered to every other day.
CO2 laser surgery.
Antihistamines? Usually ineffective
Cyclosporine therapy- 5mg/kg every day for 4-6 weeks, then every other day.
Gold salt therapies.
Alopecia, comedones, and follicular casts and crusts.
Rule out allergies, contact irritant reactions.
Demodex, Dermatophytes, Malassezia, Staphylococcus
Atopy, food intolerance, contact
Thorough history- include type of food/water bowls (avoid plastic
Seasonal to nonseasonal pruritus associated with elevated IgE.
Clinical signs include miliary dermatitis, alopecia, otitis externa, facial and cervical pruritus.
No age or breed predisposition.
Often misdiagnosed as Psychogenic alopecia??
Intradermal allergy tests:often difficult to read in the cat
Serologic allergy testing??-unreliable
Immunotherapy:75-80 have good to excellent response.
Chlorpheniramine 2-4 mg/bid