A variety of disorders can affect the upper respiratory tract of dogs; we will focus on the most common, namely laryngeal
paralysis, brachycephalic syndrome and tracheal collapse.
Laryngeal paralysis
Signalment:
- middle-aged to older, large-giant breed dogs
- males > females in most studies
Etiology:
- denervation of the recurrent laryngeal nerve results in atrophy of the cricoarytenoideus dorsalis muscle which prevent
abduction of the arytenoids cartilage leading to airway obstruction
- most dogs are bilaterally affected
- congenital in certain breeds:
o Siberian Husky
o Dalmatian
o Rottweiler
o Bull Terrier
o Bouvier des Flandres
- acquired:
o Idiopathic (most commonly)
o Trauma (including surgery)
o Diffuse neuromuscular disease (MG, polyneuropathy, polymyopathy)
o Neoplasia
o Hypothyroidism
Clinical signs:
- Consistent with upper airway disease and include:
- Stridor
- Exercise intolerance
- Voice change
- Ptyalism
- Upper airway obstruction in severely affected dogs (cyanosis, gagging, retching, collapse)
Diagnosis:
- laryngeal examination:
o either direct visualization or laryngoscopy
o generally requires anesthesia, however transnasal laryngoscopy without anesthesia has been described
o lack of abduction of arytenoid cartilages is diagnostic
o anesthetic drugs may confounded evaluation of laryngeal function
o thiopental may have the least effect on laryngeal function
o doxopram may facilitate the diagnosis in dogs that are not breathing well after induction of anesthesia
- rule out underlying and concurrent diseases:
o screening CBC, biochemistry and TT4+TSH
o thoracic radiographs (3 view 'met check')
o thorough neurologic examination
Treatment:
- medical management:
o avoidance of stress, excitement and increased environmental temperatures
o symptomatic management of upper airway obstruction in the setting of an acute crisis:
■ sedation (usually acepromazine)
■ cooling (if hyperthermic)
■ temporary anesthesia and intubation if necessary
o treatment of underlying and concurrent diseases (e.g. MG, hypothyroidism etc.)
- surgical management:
o unilateral arytenoid lateralization ("tie-back") performed most commonly since it is associated with shortest
surgical time, lowest complication rates and best overall survival time
o variety of other surgical procedures have been evaluated
o post-operative complications are common and include:
■ aspiration pneumonia ***** most commonly ******
■ continued respiratory distress
■ megaesophagus
■ vomiting
■ failure of surgical repair
■ seroma formation at the surgical site
■ unresolved coughing and/or gagging
■ persistent exercise intolerance