- 18 month old female intact Plott hound, "Donna"
- Bloody discharge that started approximately 4 1/2 weeks ago
- Discharge has increased and decreased during this time
- This is the first heat, and the owner would like to breed her
- HR, RR, temperature normal
- Weight: 57 pounds
- Bloody vulvar discharge
- Endocrine Producing Ovarian Tumor
- Cystic Ovaries.
- Exogenous Estrogens
o Is the reproductive tract normal?
o Has progesterone started to elevate?
- LH concentration: No Value!
o No more value than a cytology!
- Ultrasound of the reproductive tract
o Rarely of value, except to locate follicular like structures or tumors on the ovaries
- Karyotyping: Not indicated
- CBC, profile, urinalysis
o May be performed if indicated
- Thyroid panel
- Laparoscopic examination or exploratory laparotomy may be considered
o Rarely of value in a bitch with these signs!
Diagnostic test findings
o Normal proestrous/estrous cytology
- Proestrus - Too long for normal proestrus
- Estrus - Not typical of normal estrus
- Endocrine Producing Ovarian Tumor - Rare
- Exogenous Estrogens - Watch the clover and birth control pills!
o Diagnosis based on history (proestrus should not last over 18 days), and vaginal cytology
o History must rule out exogenous estrogens!
o 18 mcg/lb for 5 to 10 days
o 2 mg/kg up to 30 mg?
- Ovaban - Megestrol acetate
- hCG - 500 to 1000 units/animal
- Our treatment with hCG is 95% successful
- Signs decrease within 5 days and should be gone by 14 days
- Two treatments are 100% successful