Aug 01, 2011
CVC IN KANSAS CITY PROCEEDINGS
Classification of feline inflammatory liver disease(s)
Inflammatory disease has been reported to be the second most common category of liver disease in cats in the US (after hepatic lipidosis). However, within this category, there are a number of different pathologic patterns that may represent different stages of disease or even potentially separate disease conditions. This has resulted in considerable confusion about whether these various conditions should be lumped together in a broad category (cholangitis), or whether subtypes of inflammatory disease could be separated out to provide more specific and individualized information about etiology, diagnostic testing, therapeutic options, and prognosis.
Recently, the World Small Animal Veterinary Association (WSAVA) sponsored an international group of pathologists and clinicians tasked with standardizing histopathologic classification of liver disease in small animals. Among the recommendations of the WSAVA Liver Standardization Group (LSG) was that the term cholangitis be used in preference to cholangiohepatitis in cats. This recommendation was made because although inflammatory changes may occasionally extend into the hepatic parenchyma, the primary inflammatory changes are typically centered around the bile ducts. This is in contrast to dogs, in which the primary inflammatory liver disease, chronic hepatitis, directly involves the parenchyma.