Vaccines and vaccination: Issues and controversies (Part 2) (Proceedings)
A. Vaccine Selection
Today, the list of licensed vaccines for just the dog and cat is large and diverse ...approximately 110 canine vaccines and 70 feline vaccines are available. Considerable differences among vaccines for the same antigen exist. The following FAQs center on scientific issues that should be considered when selecting vaccines for individual patients.
1. Should Modified-Live vaccines be selected over Killed vaccines?When the option is available-yes. This is particularly true for cats.
Killed (inactivated) vaccines
NOTE: for some diseases, eg, leptospirosis, canine influenza, FIV, canine rabies, the only current option available is a Killed vaccine.
NOTE: Indications for the use of a Killed vaccine include: 1) vaccination of the pregnant patient (although one has to ask..."why is it necessary to vaccinate a pregnant dog or cat?") ...and 2) it is recommended that an immune compromised cat (e.g. FeLV and/or FIV positive) should only be vaccinated with a Killed vaccine. One could apply this rationale to all immune suppressed patients or patients regardless of the cause (e.g. chemotherapy). However...there are no scientific studies supporting this recommendation.
Modified-Live (attenuated) vaccines